Hematopoietic Growth Factors in Clinical Applications
نویسندگان
چکیده
منابع مشابه
Hematopoietic growth factors: ESMO Clinical Practice Guidelines for the applications.
Despite relatively high rates of low neutrophil count during standard-dose chemotherapy regimens for malignancies other than acute leukaemias, rates of FN, other complication rates and mortality rates are relatively low for most standard chemotherapies (Table 1). These rates do not justify the systematic use of haematopoietic growth factors (hGFs) such as granulocyte colony-stimulating factor (...
متن کاملHematopoietic growth factors: ESMO recommendations for the applications.
Despite relatively high rates of low neutrophil counts during standard dose chemotherapy regimens for malignancies other than acute leukemias, rates of FN, other complication rates and mortality rates are relatively low for most standard chemotherapies (Table 1). These rates do not justify the systematic use of hematopoietic growth factors (hGFs) such as granulocyte colony-stimulating factor (G...
متن کاملHematopoietic growth factors
Erythropoietin is a lineage-specific distal-acting factor that stimulates maturation of committed erythroid progenitors to become mature erythrocytes.3 Carbohydrates, rich in sialic acid, make up 30% to 40% of the 34,000-Da molecule and are essential for its secretion, stability in the circulation, and biologic activity. Many earlier-acting factors, including stem cell factor/kit ligand, interl...
متن کامل[Hematopoietic growth factors].
Haematopoietic growth factors are a family of genetically determined low molecular weight glycoproteins which regulate the proliferation and differentiation of haemopoietic cells through specific membrane receptors. GCSF and GMCSF reduce the morbidity from infections associated with the neutropenia induced by chemotherapy of onco-haematological neoplasia; EPQ totally corrects not only the anaem...
متن کاملEarly-acting hematopoietic growth factors: biology and clinical experience.
Secreted protein growth factors that stimulate the self-renewal, proliferation, and differentiation of the most primitive stem cells are among the most biologically interesting molecules and at least theoretically have diverse applications in the evolving field of regenerative medicine. Among this class of regulators, the early-acting hematopoietic growth factors and their cellular targets are ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1992
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1992.282